ofloxacin O-glucuronide structure

ofloxacin O-glucuronide

TL;DR: ofloxacin O-glucuronide (CAS 90293-81-5) is a chemical compound with molecular formula C24H28FN3O10 and molecular weight 537.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S,3S,4S,5R,6S)-6-[7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carbonyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid

Also Known As: Oflx glucuronide, Ofloxacin O-glucuronide, DL-8280 Glucuronide, Ofloxacin glucuronide, Ofloxacin Acyl-beta-D-glucuronide

CAS: 90293-81-5
Molecular Formula C24H28FN3O10
Molecular Weight 537.18 g/mol
LogP -2.5
Topological Polar Surface Area 170.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 14
Rotatable Bonds 5
Exact Mass 537.17584
Heavy Atoms 38
Complexity 990.0

Chemical Identifiers

CAS Number 90293-81-5
SMILES CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)C(=O)O)O)O)O
InChIKey GACUZKDACXKMSN-JSQDKGSLSA-N

Product Overview

ofloxacin O-glucuronide (CAS 90293-81-5), with molecular formula C24H28FN3O10 and molecular weight 537.18 g/mol. IUPAC: (2S,3S,4S,5R,6S)-6-[7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carbonyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of ofloxacin O-glucuronide

XLogP
-2.5
TPSA (Topological Polar Surface Area)
170.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
14
Rotatable Bonds
5
Heavy Atoms
38
Complexity
990.0
Exact Mass
537.17584
Monoisotopic Mass
537.17584
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of ofloxacin O-glucuronide

The XLogP value of -2.5 indicates that ofloxacin O-glucuronide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 170.0 Ų indicates high polarity, suggesting ofloxacin O-glucuronide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, ofloxacin O-glucuronide has 4 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of ofloxacin O-glucuronide?

The CAS number of ofloxacin O-glucuronide is 90293-81-5.

What is the molecular formula of ofloxacin O-glucuronide?

The molecular formula of ofloxacin O-glucuronide is C24H28FN3O10.

What is the molecular weight of ofloxacin O-glucuronide?

The molecular weight of ofloxacin O-glucuronide is 537.18 g/mol.

Where can I buy ofloxacin O-glucuronide?

You can request a quote for ofloxacin O-glucuronide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for ofloxacin O-glucuronide?

Yes, KEHONG BIO provides custom synthesis services for ofloxacin O-glucuronide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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