(E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide
TL;DR: (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide (CAS 902011-58-9) is a chemical compound with molecular formula C20H20N2O2S and molecular weight 352.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(5-ethylthiophen-2-yl)-N-methyl-N-[(2-oxo-1H-quinolin-4-yl)methyl]prop-2-enamide
Also Known As: (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide, VU0613205-1, (2E)-3-(5-ethylthiophen-2-yl)-N-[(2-hydroxyquinolin-4-yl)methyl]-N-methylprop-2-enamide, (E)-3-(5-ethylthiophen-2-yl)-N-methyl-N-[(2-oxo-1H-quinolin-4-yl)methyl]prop-2-enamide, F3375-2711
| Molecular Formula | C20H20N2O2S |
|---|---|
| Molecular Weight | 352.12 g/mol |
| LogP | 3.8238 |
| Topological Polar Surface Area | 53.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 352.12454 |
| Heavy Atoms | 25 |
| Complexity | 984.5249 |
Chemical Identifiers
| CAS Number | 902011-58-9 |
|---|---|
| SMILES | CCC1=CC=C(S1)/C=C/C(=O)N(C)CC2=CC(=O)NC3=CC=CC=C32 |
Product Overview
(E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide (CAS 902011-58-9), with molecular formula C20H20N2O2S and molecular weight 352.12 g/mol. IUPAC: (E)-3-(5-ethylthiophen-2-yl)-N-methyl-N-[(2-oxo-1H-quinolin-4-yl)methyl]prop-2-enamide.
Chemical Property Profile of (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide
Property Insights of (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide
The XLogP value of 3.8238 indicates that (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.17 Ų, (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide?
The CAS number of (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide is 902011-58-9.
What is the molecular formula of (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide?
The molecular formula of (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide is C20H20N2O2S.
What is the molecular weight of (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide?
The molecular weight of (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide is 352.12 g/mol.
Where can I buy (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide?
You can request a quote for (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(5-ethylthiophen-2-yl)-N-((2-hydroxyquinolin-4-yl)methyl)-N-methylacrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.