![2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide structure](/static/products/902/902010-47-3.png)
2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide
TL;DR: 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide (CAS 902010-47-3) is a chemical compound with molecular formula C21H22N4O2S2 and molecular weight 426.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidin-4-yl]sulfanyl]-N-(1,3-thiazol-2-yl)acetamide
Also Known As: 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide, 2-[[7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidin-4-yl]sulfanyl]-N-(1,3-thiazol-2-yl)acetamide, 2-{[7,7-dimethyl-2-(4-methylphenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide
| Molecular Formula | C21H22N4O2S2 |
|---|---|
| Molecular Weight | 426.12 g/mol |
| LogP | 4.49062 |
| Topological Polar Surface Area | 77.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 426.1184 |
| Heavy Atoms | 29 |
| Complexity | 1017.9153 |
Chemical Identifiers
| CAS Number | 902010-47-3 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=NC3=C(COC(C3)(C)C)C(=N2)SCC(=O)NC4=NC=CS4 |
Product Overview
2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide (CAS 902010-47-3), with molecular formula C21H22N4O2S2 and molecular weight 426.12 g/mol. IUPAC: 2-[[7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidin-4-yl]sulfanyl]-N-(1,3-thiazol-2-yl)acetamide.
Chemical Property Profile of 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide
Property Insights of 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide
The XLogP value of 4.49062 indicates that 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide. Following Lipinski's Rule of Five, 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide?
The CAS number of 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide is 902010-47-3.
What is the molecular formula of 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide?
The molecular formula of 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide is C21H22N4O2S2.
What is the molecular weight of 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide?
The molecular weight of 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide is 426.12 g/mol.
Where can I buy 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide?
You can request a quote for 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for 2-((7,7-dimethyl-2-(p-tolyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)thio)-N-(thiazol-2-yl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.