4egi-1
TL;DR: 4egi-1 (CAS 901787-88-0) is a chemical compound with molecular formula C18H12Cl2N4O4S and molecular weight 450.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]-3-(2-nitrophenyl)propanoic acid
Also Known As: 4egi-1, eIF4E/eIF4G Interaction Inhibitor, 2-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]-3-(2-nitrophenyl)propanoic acid, 2-{[4-(3,4-Dichloro-phenyl)-thiazol-2-yl]-hydrazono}-3-(2-nitro-phenyl)-propionic acid, (2E)-2-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]-3-(2-nitrophenyl)propanoic acid
| Molecular Formula | C18H12Cl2N4O4S |
|---|---|
| Molecular Weight | 450.00 g/mol |
| LogP | 5.1203 |
| Topological Polar Surface Area | 117.72 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 449.99564 |
| Heavy Atoms | 29 |
| Complexity | 1116.7455 |
Chemical Identifiers
| CAS Number | 901787-88-0 |
|---|---|
| SMILES | C1=CC=C(C(=C1)CC(=NNC2=NC(=CS2)C3=CC(=C(C=C3)Cl)Cl)C(=O)O)[N+](=O)[O-] |
Product Overview
4egi-1 (CAS 901787-88-0), with molecular formula C18H12Cl2N4O4S and molecular weight 450.00 g/mol. IUPAC: 2-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]-3-(2-nitrophenyl)propanoic acid.
Chemical Property Profile of 4egi-1
Property Insights of 4egi-1
The XLogP value of 5.1203 indicates that 4egi-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 117.72 Ų falls within the moderate polarity range, balancing permeability and solubility for 4egi-1. Following Lipinski's Rule of Five, 4egi-1 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4egi-1?
The CAS number of 4egi-1 is 901787-88-0.
What is the molecular formula of 4egi-1?
The molecular formula of 4egi-1 is C18H12Cl2N4O4S.
What is the molecular weight of 4egi-1?
The molecular weight of 4egi-1 is 450.00 g/mol.
Where can I buy 4egi-1?
You can request a quote for 4egi-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4egi-1?
Yes, KEHONG BIO provides custom synthesis services for 4egi-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.