H 189 structure

H 189

TL;DR: H 189 (CAS 90145-64-5) is a chemical compound with molecular formula C62H93N17O12 and molecular weight 1267.72 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-6-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(3S,4S)-3-hydroxy-4-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-[[(2S)-1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-6-methylheptanoyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid

Also Known As: H 189, H-189, H-Pro-His-Pro-Phe-His-Sta-Val-Ile-His-Lys-OH, (2S)-6-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(3S,4S)-3-hydroxy-4-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-[[(2S)-1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-6-methylheptanoyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid, ((3S,4S)-4-((S)-2-((S)-2-((S)-1-(L-prolyl-L-histidyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-3-(1H-imidazol-4-yl)propanamido)-3-hydroxy-6-methylheptanoyl)-L-valyl-L-isoleucyl-L-histidyl-L-lysine

CAS: 90145-64-5
Molecular Formula C62H93N17O12
Molecular Weight 1267.72 g/mol
LogP -0.8
Topological Polar Surface Area 435.0 Ų
Hydrogen Bond Donors 15
Hydrogen Bond Acceptors 17
Rotatable Bonds 37
Exact Mass 1267.719
Heavy Atoms 91
Complexity 2400.0

Chemical Identifiers

CAS Number 90145-64-5
SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)C[C@@H]([C@H](CC(C)C)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCCN6)O
InChIKey PZJOKAFPZVCZBJ-DJQQXEBLSA-N

Product Overview

H 189 (CAS 90145-64-5), with molecular formula C62H93N17O12 and molecular weight 1267.72 g/mol. IUPAC: (2S)-6-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(3S,4S)-3-hydroxy-4-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-[[(2S)-1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-6-methylheptanoyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of H 189

XLogP
-0.8
TPSA (Topological Polar Surface Area)
435.0
Hydrogen Bond Donors
15
Hydrogen Bond Acceptors
17
Rotatable Bonds
37
Heavy Atoms
91
Complexity
2400.0
Exact Mass
1267.719
Monoisotopic Mass
1267.719
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of H 189

The XLogP value of -0.8 indicates that H 189 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 435.0 Ų indicates high polarity, suggesting H 189 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, H 189 has 15 hydrogen bond donor(s) and 17 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of H 189?

The CAS number of H 189 is 90145-64-5.

What is the molecular formula of H 189?

The molecular formula of H 189 is C62H93N17O12.

What is the molecular weight of H 189?

The molecular weight of H 189 is 1267.72 g/mol.

Where can I buy H 189?

You can request a quote for H 189 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for H 189?

Yes, KEHONG BIO provides custom synthesis services for H 189 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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