1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one
TL;DR: 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one (CAS 900882-82-8) is a chemical compound with molecular formula C17H12ClF3N2O2 and molecular weight 368.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(2-chlorophenyl)methyl]-5-hydroxy-2-phenyl-5-(trifluoromethyl)imidazol-4-one
Also Known As: 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one, 3-(2-chlorobenzyl)-5-hydroxy-2-phenyl-5-(trifluoromethyl)-3,5-dihydro-4H-imidazol-4-one, 3-[(2-chlorophenyl)methyl]-5-hydroxy-2-phenyl-5-(trifluoromethyl)imidazol-4-one
| Molecular Formula | C17H12ClF3N2O2 |
|---|---|
| Molecular Weight | 368.05 g/mol |
| LogP | 3.3799 |
| Topological Polar Surface Area | 52.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 368.05392 |
| Heavy Atoms | 25 |
| Complexity | 839.2866 |
Chemical Identifiers
| CAS Number | 900882-82-8 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=NC(C(=O)N2CC3=CC=CC=C3Cl)(C(F)(F)F)O |
Product Overview
1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one (CAS 900882-82-8), with molecular formula C17H12ClF3N2O2 and molecular weight 368.05 g/mol. IUPAC: 3-[(2-chlorophenyl)methyl]-5-hydroxy-2-phenyl-5-(trifluoromethyl)imidazol-4-one.
Chemical Property Profile of 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one
Property Insights of 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one
The XLogP value of 3.3799 indicates that 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.9 Ų, 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
The CAS number of 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one is 900882-82-8.
What is the molecular formula of 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
The molecular formula of 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one is C17H12ClF3N2O2.
What is the molecular weight of 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
The molecular weight of 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one is 368.05 g/mol.
Where can I buy 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
You can request a quote for 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-chlorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.