1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one
TL;DR: 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one (CAS 900871-76-3) is a chemical compound with molecular formula C17H12F4N2O2 and molecular weight 352.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(4-fluorophenyl)methyl]-5-hydroxy-2-phenyl-5-(trifluoromethyl)imidazol-4-one
Also Known As: 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one, 3-(4-fluorobenzyl)-5-hydroxy-2-phenyl-5-(trifluoromethyl)-3,5-dihydro-4H-imidazol-4-one, 3-[(4-fluorophenyl)methyl]-5-hydroxy-2-phenyl-5-(trifluoromethyl)imidazol-4-one
| Molecular Formula | C17H12F4N2O2 |
|---|---|
| Molecular Weight | 352.08 g/mol |
| LogP | 2.8656 |
| Topological Polar Surface Area | 52.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 352.0835 |
| Heavy Atoms | 25 |
| Complexity | 818.7915 |
Chemical Identifiers
| CAS Number | 900871-76-3 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=NC(C(=O)N2CC3=CC=C(C=C3)F)(C(F)(F)F)O |
Product Overview
1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one (CAS 900871-76-3), with molecular formula C17H12F4N2O2 and molecular weight 352.08 g/mol. IUPAC: 3-[(4-fluorophenyl)methyl]-5-hydroxy-2-phenyl-5-(trifluoromethyl)imidazol-4-one.
Chemical Property Profile of 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one
Property Insights of 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one
The XLogP value of 2.8656 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one. With a topological polar surface area (TPSA) of 52.9 Ų, 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
The CAS number of 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one is 900871-76-3.
What is the molecular formula of 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
The molecular formula of 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one is C17H12F4N2O2.
What is the molecular weight of 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
The molecular weight of 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one is 352.08 g/mol.
Where can I buy 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
You can request a quote for 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-fluorobenzyl)-4-hydroxy-2-phenyl-4-(trifluoromethyl)-1H-imidazol-5(4H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.