Tolerzide
TL;DR: Tolerzide (CAS 90053-53-5) is a chemical compound with molecular formula C19H28ClN5O7S3 and molecular weight 569.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide;N-[4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl]methanesulfonamide
Also Known As: Tolerzide, Hydrochlorothiazide mixture with sotalol, 6-chloro-1,1-dioxo-3,4-dihydro-2H-1, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide, mixt. with N-(4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)phenyl)methanesulfonamide, 6-Chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~,2,4-benzothiadiazine-7-sulfonamide--N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide (1/1)
| Molecular Formula | C19H28ClN5O7S3 |
|---|---|
| Molecular Weight | 569.08 g/mol |
| LogP | 0.7382 |
| Topological Polar Surface Area | 222.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 7 |
| Exact Mass | 569.0839 |
| Heavy Atoms | 35 |
| Complexity | 824.0 |
Chemical Identifiers
| CAS Number | 90053-53-5 |
|---|---|
| SMILES | CC(C)NCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl |
| InChIKey | OZTXBYYBRCIFHI-UHFFFAOYSA-N |
Product Overview
Tolerzide (CAS 90053-53-5), with molecular formula C19H28ClN5O7S3 and molecular weight 569.08 g/mol. IUPAC: 6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide;N-[4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl]methanesulfonamide.
Chemical Property Profile of Tolerzide
Property Insights of Tolerzide
The XLogP value of 0.7382 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tolerzide. The TPSA of 222.0 Ų indicates high polarity, suggesting Tolerzide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tolerzide has 6 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tolerzide?
The CAS number of Tolerzide is 90053-53-5.
What is the molecular formula of Tolerzide?
The molecular formula of Tolerzide is C19H28ClN5O7S3.
What is the molecular weight of Tolerzide?
The molecular weight of Tolerzide is 569.08 g/mol.
Where can I buy Tolerzide?
You can request a quote for Tolerzide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tolerzide?
Yes, KEHONG BIO provides custom synthesis services for Tolerzide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.