Betamethasone sodium structure

Betamethasone sodium

TL;DR: Betamethasone sodium (CAS 9005-10-1) is a chemical compound with molecular formula C22H27FNa2O5 and molecular weight 436.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

disodium;(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-11,17-diolate

Also Known As: Betamethasone sodium, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, disodium salt, (11beta,16beta)-, disodium(11, A,16, A)-9-fluoro-21-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-11,17-diolate

CAS: 9005-10-1
Molecular Formula C22H27FNa2O5
Molecular Weight 436.16 g/mol
LogP -5.3603
Topological Polar Surface Area 100.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 2
Exact Mass 436.1638
Heavy Atoms 30
Complexity 805.0

Chemical Identifiers

CAS Number 9005-10-1
SMILES C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)[O-])C)[O-])F)C.[Na+].[Na+]
InChIKey CUAKZZUNMDTHBQ-LWCNAHDDSA-N

Product Overview

Betamethasone sodium (CAS 9005-10-1), with molecular formula C22H27FNa2O5 and molecular weight 436.16 g/mol. IUPAC: disodium;(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-11,17-diolate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Betamethasone sodium

XLogP
-5.3603
TPSA (Topological Polar Surface Area)
100.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
2
Heavy Atoms
30
Complexity
805.0
Exact Mass
436.1638
Monoisotopic Mass
436.1638
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Betamethasone sodium

The XLogP value of -5.3603 indicates that Betamethasone sodium is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 100.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Betamethasone sodium. Following Lipinski's Rule of Five, Betamethasone sodium has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Betamethasone sodium?

The CAS number of Betamethasone sodium is 9005-10-1.

What is the molecular formula of Betamethasone sodium?

The molecular formula of Betamethasone sodium is C22H27FNa2O5.

What is the molecular weight of Betamethasone sodium?

The molecular weight of Betamethasone sodium is 436.16 g/mol.

Where can I buy Betamethasone sodium?

You can request a quote for Betamethasone sodium directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Betamethasone sodium?

Yes, KEHONG BIO provides custom synthesis services for Betamethasone sodium and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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