![2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile structure](/static/products/900/900283-88-7.png)
2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile
TL;DR: 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile (CAS 900283-88-7) is a chemical compound with molecular formula C22H16ClN5O2 and molecular weight 417.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2'-amino-1'-(5-chloro-2-pyridinyl)-2,5'-dioxospiro[1H-indole-3,4'-7,8-dihydro-6H-quinoline]-3'-carbonitrile
Also Known As: 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile, 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-5',6',7',8'-tetrahydro-1'H-spiro[indoline-3,4'-quinoline]-3'-carbonitrile, 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxospiro[1H-indole-3,4'-7,8-dihydro-6H-quinoline]-3'-carbonitrile
| Molecular Formula | C22H16ClN5O2 |
|---|---|
| Molecular Weight | 417.10 g/mol |
| LogP | 3.14608 |
| Topological Polar Surface Area | 112.11 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 417.09924 |
| Heavy Atoms | 30 |
| Complexity | 1224.8341 |
Chemical Identifiers
| CAS Number | 900283-88-7 |
|---|---|
| SMILES | C1CC2=C(C(=O)C1)C3(C4=CC=CC=C4NC3=O)C(=C(N2C5=NC=C(C=C5)Cl)N)C#N |
Product Overview
2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile (CAS 900283-88-7), with molecular formula C22H16ClN5O2 and molecular weight 417.10 g/mol. IUPAC: 2'-amino-1'-(5-chloro-2-pyridinyl)-2,5'-dioxospiro[1H-indole-3,4'-7,8-dihydro-6H-quinoline]-3'-carbonitrile.
Chemical Property Profile of 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile
Property Insights of 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile
The XLogP value of 3.14608 indicates that 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 112.11 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile. Following Lipinski's Rule of Five, 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile?
The CAS number of 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile is 900283-88-7.
What is the molecular formula of 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile?
The molecular formula of 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile is C22H16ClN5O2.
What is the molecular weight of 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile?
The molecular weight of 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile is 417.10 g/mol.
Where can I buy 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile?
You can request a quote for 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile?
Yes, KEHONG BIO provides custom synthesis services for 2'-amino-1'-(5-chloropyridin-2-yl)-2,5'-dioxo-1,2,5',6',7',8'-hexahydro-1'H-spiro[indole-3,4'-quinoline]-3'-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.