F2743-0189
TL;DR: F2743-0189 (CAS 899753-93-6) is a chemical compound with molecular formula C20H13F5N2O2 and molecular weight 408.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(3-fluorophenyl)methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-2-oxopyridine-3-carboxamide
Also Known As: F2743-0189, N-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[(3-fluorophenyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxamide, N-(4-fluoro-3-(trifluoromethyl)phenyl)-1-(3-fluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide, 1-[(3-fluorophenyl)methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-2-oxopyridine-3-carboxamide
| Molecular Formula | C20H13F5N2O2 |
|---|---|
| Molecular Weight | 408.09 g/mol |
| LogP | 4.4459 |
| Topological Polar Surface Area | 51.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 408.08972 |
| Heavy Atoms | 29 |
| Complexity | 1122.3398 |
Chemical Identifiers
| CAS Number | 899753-93-6 |
|---|---|
| SMILES | C1=CC(=CC(=C1)F)CN2C=CC=C(C2=O)C(=O)NC3=CC(=C(C=C3)F)C(F)(F)F |
Product Overview
F2743-0189 (CAS 899753-93-6), with molecular formula C20H13F5N2O2 and molecular weight 408.09 g/mol. IUPAC: 1-[(3-fluorophenyl)methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-2-oxopyridine-3-carboxamide.
Chemical Property Profile of F2743-0189
Property Insights of F2743-0189
The XLogP value of 4.4459 indicates that F2743-0189 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.1 Ų, F2743-0189 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F2743-0189 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F2743-0189?
The CAS number of F2743-0189 is 899753-93-6.
What is the molecular formula of F2743-0189?
The molecular formula of F2743-0189 is C20H13F5N2O2.
What is the molecular weight of F2743-0189?
The molecular weight of F2743-0189 is 408.09 g/mol.
Where can I buy F2743-0189?
You can request a quote for F2743-0189 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F2743-0189?
Yes, KEHONG BIO provides custom synthesis services for F2743-0189 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.