Bis-sulfone NHS Ester structure

Bis-sulfone NHS Ester

TL;DR: Bis-sulfone NHS Ester (CAS 899452-51-8) is a chemical compound with molecular formula C29H27NO9S2 and molecular weight 597.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2,5-dioxopyrrolidin-1-yl) 4-[3-(4-methylphenyl)sulfonyl-2-[(4-methylphenyl)sulfonylmethyl]propanoyl]benzoate

Also Known As: Bis-sulfone NHS Ester, nchembio786-comp2, 2,5-Dioxopyrrolidin-1-yl 4-(3-tosyl-2-(tosylmethyl)propanoyl)benzoate, 4-[2,2-bis[(p-tolylsulfonyl)-methyl]acetyl]benzoic acid-N-hydroxy succinimidyl ester, 4-[2,2-bis[(p-tolylsulfonyl)-methyl]acetyl]benzoic acid N-succinimidyl ester

CAS: 899452-51-8
Molecular Formula C29H27NO9S2
Molecular Weight 597.11 g/mol
LogP 3.27094
Topological Polar Surface Area 149.03 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 9
Rotatable Bonds 10
Exact Mass 597.11273
Heavy Atoms 41
Complexity 1616.688

Chemical Identifiers

CAS Number 899452-51-8
SMILES CC1=CC=C(C=C1)S(=O)(=O)CC(CS(=O)(=O)C2=CC=C(C=C2)C)C(=O)C3=CC=C(C=C3)C(=O)ON4C(=O)CCC4=O

Product Overview

Bis-sulfone NHS Ester (CAS 899452-51-8), with molecular formula C29H27NO9S2 and molecular weight 597.11 g/mol. IUPAC: (2,5-dioxopyrrolidin-1-yl) 4-[3-(4-methylphenyl)sulfonyl-2-[(4-methylphenyl)sulfonylmethyl]propanoyl]benzoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Bis-sulfone NHS Ester

XLogP
3.27094
TPSA (Topological Polar Surface Area)
149.03
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
9
Rotatable Bonds
10
Heavy Atoms
41
Complexity
1616.688
Exact Mass
597.11273
Monoisotopic Mass
597.11273
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Bis-sulfone NHS Ester

The XLogP value of 3.27094 indicates that Bis-sulfone NHS Ester is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 149.03 Ų indicates high polarity, suggesting Bis-sulfone NHS Ester may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bis-sulfone NHS Ester has 0 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Bis-sulfone NHS Ester?

The CAS number of Bis-sulfone NHS Ester is 899452-51-8.

What is the molecular formula of Bis-sulfone NHS Ester?

The molecular formula of Bis-sulfone NHS Ester is C29H27NO9S2.

What is the molecular weight of Bis-sulfone NHS Ester?

The molecular weight of Bis-sulfone NHS Ester is 597.11 g/mol.

Where can I buy Bis-sulfone NHS Ester?

You can request a quote for Bis-sulfone NHS Ester directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Bis-sulfone NHS Ester?

Yes, KEHONG BIO provides custom synthesis services for Bis-sulfone NHS Ester and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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