![(2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one structure](/static/products/899/899394-06-0.png)
(2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one
TL;DR: (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one (CAS 899394-06-0) is a chemical compound with molecular formula C27H33N3O4 and molecular weight 463.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-1-(3,4-dimethoxyphenyl)-3-[1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]indol-3-yl]prop-2-en-1-one
Also Known As: (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one, (E)-1-(3,4-Dimethoxy-phenyl)-3-{1-[2-hydroxy-3-(4-methyl-piperazin-1-yl)-propyl]-1H-indol-3-yl}-propeno ne, (E)-1-(3,4-dimethoxyphenyl)-3-[1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]indol-3-yl]prop-2-en-1-one, (E)-1-(3,4-dimethoxyphenyl)-3-(1-(2-hydroxy-3-(4-methylpiperazin-1-yl)propyl)-1H-indol-3-yl)prop-2-en-1-one, (E)-1-(3,4-dimethoxyphenyl)-3-[1-[2-hydroxy-3-(4-methyl-1-piperazinyl)propyl]-3-indolyl]-2-propen-1-one
| Molecular Formula | C27H33N3O4 |
|---|---|
| Molecular Weight | 463.25 g/mol |
| LogP | 3.1629 |
| Topological Polar Surface Area | 67.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 463.2471 |
| Heavy Atoms | 34 |
| Complexity | 1161.8916 |
Chemical Identifiers
| CAS Number | 899394-06-0 |
|---|---|
| SMILES | CN1CCN(CC1)CC(CN2C=C(C3=CC=CC=C32)/C=C/C(=O)C4=CC(=C(C=C4)OC)OC)O |
Product Overview
(2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one (CAS 899394-06-0), with molecular formula C27H33N3O4 and molecular weight 463.25 g/mol. IUPAC: (E)-1-(3,4-dimethoxyphenyl)-3-[1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]indol-3-yl]prop-2-en-1-one.
Chemical Property Profile of (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one
Property Insights of (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one
The XLogP value of 3.1629 indicates that (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.17 Ų falls within the moderate polarity range, balancing permeability and solubility for (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one. Following Lipinski's Rule of Five, (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one?
The CAS number of (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one is 899394-06-0.
What is the molecular formula of (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one?
The molecular formula of (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one is C27H33N3O4.
What is the molecular weight of (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one?
The molecular weight of (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one is 463.25 g/mol.
Where can I buy (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one?
You can request a quote for (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one?
Yes, KEHONG BIO provides custom synthesis services for (2E)-1-(3,4-dimethoxyphenyl)-3-{1-[2-hydroxy-3-(4-methylpiperazin-1-yl)propyl]-1H-indol-3-yl}prop-2-en-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.