1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline
TL;DR: 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline (CAS 899376-27-3) is a chemical compound with molecular formula C20H17FN4 and molecular weight 332.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(1,3-dihydroisoindol-2-yl)-5-fluoropyrimidin-4-yl]-2,3-dihydroindole
Also Known As: 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline, 1-[2-(1,3-dihydro-2H-isoindol-2-yl)-5-fluoropyrimidin-4-yl]-2,3-dihydro-1H-indole, 1-[2-(1,3-dihydroisoindol-2-yl)-5-fluoropyrimidin-4-yl]-2,3-dihydroindole
| Molecular Formula | C20H17FN4 |
|---|---|
| Molecular Weight | 332.14 g/mol |
| LogP | 3.8301 |
| Topological Polar Surface Area | 32.26 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 332.14374 |
| Heavy Atoms | 25 |
| Complexity | 930.9311 |
Chemical Identifiers
| CAS Number | 899376-27-3 |
|---|---|
| SMILES | C1CN(C2=CC=CC=C21)C3=NC(=NC=C3F)N4CC5=CC=CC=C5C4 |
Product Overview
1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline (CAS 899376-27-3), with molecular formula C20H17FN4 and molecular weight 332.14 g/mol. IUPAC: 1-[2-(1,3-dihydroisoindol-2-yl)-5-fluoropyrimidin-4-yl]-2,3-dihydroindole.
Chemical Property Profile of 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline
Property Insights of 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline
The XLogP value of 3.8301 indicates that 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.26 Ų, 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline?
The CAS number of 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline is 899376-27-3.
What is the molecular formula of 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline?
The molecular formula of 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline is C20H17FN4.
What is the molecular weight of 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline?
The molecular weight of 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline is 332.14 g/mol.
Where can I buy 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline?
You can request a quote for 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline?
Yes, KEHONG BIO provides custom synthesis services for 1-(5-fluoro-2-(isoindolin-2-yl)pyrimidin-4-yl)indoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.