1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine
TL;DR: 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine (CAS 898922-07-1) is a chemical compound with molecular formula C18H19N3O2S3 and molecular weight 405.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-methyl-4-phenyl-2-(4-thiophen-2-ylsulfonylpiperazin-1-yl)-1,3-thiazole
Also Known As: 5-methyl-4-phenyl-2-(4-(thiophen-2-ylsulfonyl)piperazin-1-yl)thiazole, 5-methyl-4-phenyl-2-(4-thiophen-2-ylsulfonylpiperazin-1-yl)-1,3-thiazole, 1-(5-methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine
| Molecular Formula | C18H19N3O2S3 |
|---|---|
| Molecular Weight | 405.06 g/mol |
| LogP | 3.69092 |
| Topological Polar Surface Area | 53.51 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 405.06393 |
| Heavy Atoms | 26 |
| Complexity | 974.13 |
Chemical Identifiers
| CAS Number | 898922-07-1 |
|---|---|
| SMILES | CC1=C(N=C(S1)N2CCN(CC2)S(=O)(=O)C3=CC=CS3)C4=CC=CC=C4 |
Product Overview
1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine (CAS 898922-07-1), with molecular formula C18H19N3O2S3 and molecular weight 405.06 g/mol. IUPAC: 5-methyl-4-phenyl-2-(4-thiophen-2-ylsulfonylpiperazin-1-yl)-1,3-thiazole.
Chemical Property Profile of 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine
Property Insights of 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine
The XLogP value of 3.69092 indicates that 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.51 Ų, 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine?
The CAS number of 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine is 898922-07-1.
What is the molecular formula of 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine?
The molecular formula of 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine is C18H19N3O2S3.
What is the molecular weight of 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine?
The molecular weight of 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine is 405.06 g/mol.
Where can I buy 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine?
You can request a quote for 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-4-(thiophen-2-ylsulfonyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.