(2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
TL;DR: (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone (CAS 898159-18-7) is a chemical compound with molecular formula C15H14ClFN4O and molecular weight 320.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2-chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
Also Known As: (2-chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone, 2-chloro-4-fluorophenyl 4-pyrimidin-2-ylpiperazinyl ketone, (2-CHLORO-4-FLUOROPHENYL)[4-(2-PYRIMIDINYL)PIPERAZINO]METHANONE, (2-chloro-4-fluorophenyl)[4-(pyrimidin-2-yl)piperazin-1-yl]methanone
| Molecular Formula | C15H14ClFN4O |
|---|---|
| Molecular Weight | 320.08 g/mol |
| LogP | 2.2315 |
| Topological Polar Surface Area | 49.33 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 320.084 |
| Heavy Atoms | 22 |
| Complexity | 674.4976 |
Chemical Identifiers
| CAS Number | 898159-18-7 |
|---|---|
| SMILES | C1CN(CCN1C2=NC=CC=N2)C(=O)C3=C(C=C(C=C3)F)Cl |
Product Overview
(2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone (CAS 898159-18-7), with molecular formula C15H14ClFN4O and molecular weight 320.08 g/mol. IUPAC: (2-chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone.
Chemical Property Profile of (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
Property Insights of (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
The XLogP value of 2.2315 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone. With a topological polar surface area (TPSA) of 49.33 Ų, (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
The CAS number of (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone is 898159-18-7.
What is the molecular formula of (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
The molecular formula of (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone is C15H14ClFN4O.
What is the molecular weight of (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
The molecular weight of (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone is 320.08 g/mol.
Where can I buy (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
You can request a quote for (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone?
Yes, KEHONG BIO provides custom synthesis services for (2-Chloro-4-fluorophenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.