Manganese bleomycin
TL;DR: Manganese bleomycin (CAS 89725-97-3) is a chemical compound with molecular formula C55H83MnN20O21S2+2 and molecular weight 1478.49 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-N-[1-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[[5-[[1-[2-[4-[4-[4-(diaminomethylideneamino)butylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]-5-methylpyrimidine-4-carboximidate;manganese(3+)
Also Known As: Manganese bleomycin, Mn-Bleomycin, Mn(III)-Bleomycin, Manganese(2+), (N1-(4-((aminoiminomethyl)amino)butyl)bleomycinamidato)-, 6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-N-[1-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[[5-[[1-[2-[4-[4-[4-(diaminomethylideneamino)butylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]-5-methylpyrimidine-4-carboximidate;manganese(3+)
| Molecular Formula | C55H83MnN20O21S2+2 |
|---|---|
| Molecular Weight | 1478.49 g/mol |
| LogP | -9.54338 |
| Topological Polar Surface Area | 697.79 Ų |
| Hydrogen Bond Donors | 21 |
| Hydrogen Bond Acceptors | 33 |
| Rotatable Bonds | 36 |
| Exact Mass | 1478.4863 |
| Heavy Atoms | 99 |
| Complexity | 3409.039 |
Chemical Identifiers
| CAS Number | 89725-97-3 |
|---|---|
| SMILES | CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCCN=C(N)N)O)[O-].[Mn+3] |
Product Overview
Manganese bleomycin (CAS 89725-97-3), with molecular formula C55H83MnN20O21S2+2 and molecular weight 1478.49 g/mol. IUPAC: 6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-N-[1-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[[5-[[1-[2-[4-[4-[4-(diaminomethylideneamino)butylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]-5-methylpyrimidine-4-carboximidate;manganese(3+).
Chemical Property Profile of Manganese bleomycin
Property Insights of Manganese bleomycin
The XLogP value of -9.54338 indicates that Manganese bleomycin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 697.79 Ų indicates high polarity, suggesting Manganese bleomycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Manganese bleomycin has 21 hydrogen bond donor(s) and 33 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Manganese bleomycin?
The CAS number of Manganese bleomycin is 89725-97-3.
What is the molecular formula of Manganese bleomycin?
The molecular formula of Manganese bleomycin is C55H83MnN20O21S2+2.
What is the molecular weight of Manganese bleomycin?
The molecular weight of Manganese bleomycin is 1478.49 g/mol.
Where can I buy Manganese bleomycin?
You can request a quote for Manganese bleomycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Manganese bleomycin?
Yes, KEHONG BIO provides custom synthesis services for Manganese bleomycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.