5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one
TL;DR: 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one (CAS 896649-52-8) is a chemical compound with molecular formula C21H15ClN2O2S and molecular weight 394.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indol-2-one
Also Known As: 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indol-2-one, 5'-chloro-3'-hydroxy-1'-(thiophen-2-ylmethyl)-1',3'-dihydro-1H,2'H-3,3'-biindol-2'-one, 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one
| Molecular Formula | C21H15ClN2O2S |
|---|---|
| Molecular Weight | 394.05 g/mol |
| LogP | 4.6655 |
| Topological Polar Surface Area | 56.33 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 394.0543 |
| Heavy Atoms | 27 |
| Complexity | 1168.1246 |
Chemical Identifiers
| CAS Number | 896649-52-8 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2)C3(C4=C(C=CC(=C4)Cl)N(C3=O)CC5=CC=CS5)O |
Product Overview
5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one (CAS 896649-52-8), with molecular formula C21H15ClN2O2S and molecular weight 394.05 g/mol. IUPAC: 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indol-2-one.
Chemical Property Profile of 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one
Property Insights of 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one
The XLogP value of 4.6655 indicates that 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.33 Ų, 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one?
The CAS number of 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one is 896649-52-8.
What is the molecular formula of 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one?
The molecular formula of 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one is C21H15ClN2O2S.
What is the molecular weight of 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one?
The molecular weight of 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one is 394.05 g/mol.
Where can I buy 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one?
You can request a quote for 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 5-chloro-3-hydroxy-3-(1H-indol-3-yl)-1-(thiophen-2-ylmethyl)indolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.