G418
TL;DR: G418 (CAS 89601-09-2) is a chemical compound with molecular formula C20H40N4O10 and molecular weight 496.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
G418
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-[(1R)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
Also Known As: geneticin, antibiotic G 418, antibiotic G-418, Antibiotic G418, G418
| Molecular Formula | C20H40N4O10 |
|---|---|
| Molecular Weight | 496.27 g/mol |
| LogP | -5.8 |
| Topological Polar Surface Area | 248.0 Ų |
| Hydrogen Bond Donors | 10 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 6 |
| Exact Mass | 496.27444 |
| Heavy Atoms | 34 |
| Complexity | 681.0 |
Chemical Identifiers
| CAS Number | 89601-09-2 |
|---|---|
| SMILES | C[C@H]([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)O)O)O |
| InChIKey | BRZYSWJRSDMWLG-DJWUNRQOSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
G418 (CAS 89601-09-2), with molecular formula C20H40N4O10 and molecular weight 496.27 g/mol. IUPAC: (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-[(1R)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol.
Chemical Property Profile of G418
Property Insights of G418
The XLogP value of -5.8 indicates that G418 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 248.0 Ų indicates high polarity, suggesting G418 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, G418 has 10 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of G418?
The CAS number of G418 is 89601-09-2.
What is the molecular formula of G418?
The molecular formula of G418 is C20H40N4O10.
What is the molecular weight of G418?
The molecular weight of G418 is 496.27 g/mol.
Where can I buy G418?
You can request a quote for G418 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for G418?
Yes, KEHONG BIO provides custom synthesis services for G418 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.