N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide
TL;DR: N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide (CAS 895730-20-8) is a chemical compound with molecular formula C8H7F3N2O2S and molecular weight 252.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide
Also Known As: N-(3-ACETYL-4-METHYL(2,5-THIAZOLYL))-2,2,2-TRIFLUOROETHANAMIDE, N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide, N-(5-acetyl-4-methyl-thiazol-2-yl)-2,2,2-trifluoro-acetamide, N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoro-acetamide
| Molecular Formula | C8H7F3N2O2S |
|---|---|
| Molecular Weight | 252.02 g/mol |
| LogP | 2.15492 |
| Topological Polar Surface Area | 59.06 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 252.01804 |
| Heavy Atoms | 16 |
| Complexity | 438.9821 |
Chemical Identifiers
| CAS Number | 895730-20-8 |
|---|---|
| SMILES | CC1=C(SC(=N1)NC(=O)C(F)(F)F)C(=O)C |
Product Overview
N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide (CAS 895730-20-8), with molecular formula C8H7F3N2O2S and molecular weight 252.02 g/mol. IUPAC: N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide.
Chemical Property Profile of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide
Property Insights of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide
The XLogP value of 2.15492 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide. With a topological polar surface area (TPSA) of 59.06 Ų, N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide?
The CAS number of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide is 895730-20-8.
What is the molecular formula of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide?
The molecular formula of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide is C8H7F3N2O2S.
What is the molecular weight of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide?
The molecular weight of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide is 252.02 g/mol.
Where can I buy N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide?
You can request a quote for N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-2,2,2-trifluoroacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.