4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole
TL;DR: 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole (CAS 89427-27-0) is a chemical compound with molecular formula C8HCl2F5N2 and molecular weight 289.94 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5,7-dichloro-4,6-difluoro-2-(trifluoromethyl)-1H-benzimidazole
Also Known As: C8HCl2F5N2, 5,7-Dichloro-4,6-difluoro-2-(trifluoromethyl)benzimidazole, 1H-Benzimidazole, 4,6-dichloro-5,7-difluoro-2-(trifluoromethyl)-, Benzimidazole, 5,7-dichloro-4,6-difluoro-2-(trifluoromethyl)-, 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole
| Molecular Formula | C8HCl2F5N2 |
|---|---|
| Molecular Weight | 289.94 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 28.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 0 |
| Exact Mass | 289.9437 |
| Heavy Atoms | 17 |
| Complexity | 302.0 |
Chemical Identifiers
| CAS Number | 89427-27-0 |
|---|---|
| SMILES | C12=C(C(=C(C(=C1Cl)F)Cl)F)N=C(N2)C(F)(F)F |
| InChIKey | JQGLVTOSBVIPTM-UHFFFAOYSA-N |
Product Overview
4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole (CAS 89427-27-0), with molecular formula C8HCl2F5N2 and molecular weight 289.94 g/mol. IUPAC: 5,7-dichloro-4,6-difluoro-2-(trifluoromethyl)-1H-benzimidazole.
Chemical Property Profile of 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole
Property Insights of 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole
The XLogP value of 3.5 indicates that 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.7 Ų, 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole?
The CAS number of 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole is 89427-27-0.
What is the molecular formula of 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole?
The molecular formula of 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole is C8HCl2F5N2.
What is the molecular weight of 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole?
The molecular weight of 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole is 289.94 g/mol.
Where can I buy 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole?
You can request a quote for 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole?
Yes, KEHONG BIO provides custom synthesis services for 4,6-Dichloro-5,7-difluoro-2-(trifluoromethyl)-1H-benzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.