7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole
TL;DR: 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole (CAS 89426-97-1) is a chemical compound with molecular formula C8H3ClF4N2 and molecular weight 237.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-6-fluoro-2-(trifluoromethyl)-1H-benzimidazole
Also Known As: BENZIMIDAZOLE, 4-CHLORO-6-FLUORO-2-(TRIFLUOROMETHYL)-, 4-chloro-6-fluoro-2-(trifluoromethyl)-1H-benzimidazole, 4-Chloro-6-fluoro -2-(trifluoromethyl)-1H-benzimidazole, 4-Chloro-6-fluoro-2-(trifluoromethyl)benzimidazole, 1H-Benzimidazole, 7-chloro-5-fluoro-2-(trifluoromethyl)-
| Molecular Formula | C8H3ClF4N2 |
|---|---|
| Molecular Weight | 237.99 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 28.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 0 |
| Exact Mass | 237.9921 |
| Heavy Atoms | 15 |
| Complexity | 247.0 |
Chemical Identifiers
| CAS Number | 89426-97-1 |
|---|---|
| SMILES | C1=C(C=C(C2=C1NC(=N2)C(F)(F)F)Cl)F |
| InChIKey | BGXMIJJBIRSJKL-UHFFFAOYSA-N |
Product Overview
7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole (CAS 89426-97-1), with molecular formula C8H3ClF4N2 and molecular weight 237.99 g/mol. IUPAC: 4-chloro-6-fluoro-2-(trifluoromethyl)-1H-benzimidazole.
Chemical Property Profile of 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole
Property Insights of 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole
The XLogP value of 3.0 indicates that 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.7 Ų, 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole?
The CAS number of 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole is 89426-97-1.
What is the molecular formula of 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole?
The molecular formula of 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole is C8H3ClF4N2.
What is the molecular weight of 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole?
The molecular weight of 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole is 237.99 g/mol.
Where can I buy 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole?
You can request a quote for 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole?
Yes, KEHONG BIO provides custom synthesis services for 7-Chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.