8-Hydroxy-4-methyl-3,4-dihydroxycoumarin structure

8-Hydroxy-4-methyl-3,4-dihydroxycoumarin

TL;DR: 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin (CAS 894-76-8) is a chemical compound with molecular formula C10H10O3 and molecular weight 178.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

8-hydroxy-4-methyl-3,4-dihydrochromen-2-one

Also Known As: 8-Hmdhc, 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin, 8-hydroxy-4-methyl-3,4-dihydrochromen-2-one, 2h-1-benzopyran-2-one, 3,4-dihydro-8-hydroxy-4-methyl-,(-)-, 8-Hydroxy-4-methyl-3,4-dihydro-2H-1-benzopyran-2-one

CAS: 894-76-8
Molecular Formula C10H10O3
Molecular Weight 178.06 g/mol
LogP 1.6
Topological Polar Surface Area 46.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 0
Exact Mass 178.06299
Heavy Atoms 13
Complexity 214.0

Chemical Identifiers

CAS Number 894-76-8
SMILES CC1CC(=O)OC2=C1C=CC=C2O
InChIKey MEUPTAWCOWQTAC-UHFFFAOYSA-N

Product Overview

8-Hydroxy-4-methyl-3,4-dihydroxycoumarin (CAS 894-76-8), with molecular formula C10H10O3 and molecular weight 178.06 g/mol. IUPAC: 8-hydroxy-4-methyl-3,4-dihydrochromen-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin

XLogP
1.6
TPSA (Topological Polar Surface Area)
46.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
0
Heavy Atoms
13
Complexity
214.0
Exact Mass
178.06299
Monoisotopic Mass
178.06299
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin

The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin. With a topological polar surface area (TPSA) of 46.5 Ų, 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin?

The CAS number of 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin is 894-76-8.

What is the molecular formula of 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin?

The molecular formula of 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin is C10H10O3.

What is the molecular weight of 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin?

The molecular weight of 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin is 178.06 g/mol.

Where can I buy 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin?

You can request a quote for 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin?

Yes, KEHONG BIO provides custom synthesis services for 8-Hydroxy-4-methyl-3,4-dihydroxycoumarin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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