2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine
TL;DR: 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine (CAS 893772-23-1) is a chemical compound with molecular formula C7H7ClFN3 and molecular weight 187.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine
Also Known As: 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine, 4-Pyrimidinamine, 2-chloro-N-cyclopropyl-5-fluoro-, (2-Chloro-5-fluoro-pyrimidin-4-yl)-cyclopropyl-amine, (2-chloro-5-fluoropyrimidin-4-yl)cyclopropylamine, 2-Chloro-n-cyclopropyl-5-fluoro-4-pyrimidinamine
| Molecular Formula | C7H7ClFN3 |
|---|---|
| Molecular Weight | 187.03 g/mol |
| LogP | 1.8434 |
| Topological Polar Surface Area | 37.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 187.03125 |
| Heavy Atoms | 12 |
| Complexity | 300.703 |
Chemical Identifiers
| CAS Number | 893772-23-1 |
|---|---|
| SMILES | C1CC1NC2=NC(=NC=C2F)Cl |
Product Overview
2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine (CAS 893772-23-1), with molecular formula C7H7ClFN3 and molecular weight 187.03 g/mol. IUPAC: 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine.
Chemical Property Profile of 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine
Property Insights of 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine
The XLogP value of 1.8434 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine. With a topological polar surface area (TPSA) of 37.81 Ų, 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine?
The CAS number of 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine is 893772-23-1.
What is the molecular formula of 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine?
The molecular formula of 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine is C7H7ClFN3.
What is the molecular weight of 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine?
The molecular weight of 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine is 187.03 g/mol.
Where can I buy 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine?
You can request a quote for 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine?
Yes, KEHONG BIO provides custom synthesis services for 2-chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.