1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
TL;DR: 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone (CAS 892720-72-8) is a chemical compound with molecular formula C19H21N5O and molecular weight 335.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Also Known As: 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone, 1-(2-methyl-1H-indol-3-yl)-2-(4-(pyrimidin-2-yl)piperazin-1-yl)ethanone, 1-(2-methyl-1H-indol-3-yl)-2-[4-(pyrimidin-2-yl)piperazin-1-yl]ethanone
| Molecular Formula | C19H21N5O |
|---|---|
| Molecular Weight | 335.17 g/mol |
| LogP | 2.27122 |
| Topological Polar Surface Area | 65.12 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 335.17462 |
| Heavy Atoms | 25 |
| Complexity | 881.22565 |
Chemical Identifiers
| CAS Number | 892720-72-8 |
|---|---|
| SMILES | CC1=C(C2=CC=CC=C2N1)C(=O)CN3CCN(CC3)C4=NC=CC=N4 |
Product Overview
1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone (CAS 892720-72-8), with molecular formula C19H21N5O and molecular weight 335.17 g/mol. IUPAC: 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone.
Chemical Property Profile of 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Property Insights of 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
The XLogP value of 2.27122 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone. The TPSA of 65.12 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone. Following Lipinski's Rule of Five, 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
The CAS number of 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone is 892720-72-8.
What is the molecular formula of 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
The molecular formula of 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone is C19H21N5O.
What is the molecular weight of 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
The molecular weight of 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone is 335.17 g/mol.
Where can I buy 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
You can request a quote for 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-methyl-1H-indol-3-yl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.