![(4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one structure](/static/products/892/892627-76-8.png)
(4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
TL;DR: (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (CAS 892627-76-8) is a chemical compound with molecular formula C30H28N4O3 and molecular weight 492.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-4-[[1-[3-(4-acetylanilino)-2-hydroxypropyl]indol-3-yl]methylidene]-5-methyl-2-phenylpyrazol-3-one
Also Known As: (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, (4E)-4-[[1-[3-(4-acetylanilino)-2-hydroxypropyl]indol-3-yl]methylidene]-5-methyl-2-phenylpyrazol-3-one, (E)-4-((1-(3-((4-acetylphenyl)amino)-2-hydroxypropyl)-1H-indol-3-yl)methylene)-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one
| Molecular Formula | C30H28N4O3 |
|---|---|
| Molecular Weight | 492.22 g/mol |
| LogP | 5.123 |
| Topological Polar Surface Area | 86.93 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 492.21616 |
| Heavy Atoms | 37 |
| Complexity | 1517.7349 |
Chemical Identifiers
| CAS Number | 892627-76-8 |
|---|---|
| SMILES | CC\1=NN(C(=O)/C1=C/C2=CN(C3=CC=CC=C32)CC(CNC4=CC=C(C=C4)C(=O)C)O)C5=CC=CC=C5 |
Product Overview
(4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (CAS 892627-76-8), with molecular formula C30H28N4O3 and molecular weight 492.22 g/mol. IUPAC: (4E)-4-[[1-[3-(4-acetylanilino)-2-hydroxypropyl]indol-3-yl]methylidene]-5-methyl-2-phenylpyrazol-3-one.
Chemical Property Profile of (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
Property Insights of (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
The XLogP value of 5.123 indicates that (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.93 Ų falls within the moderate polarity range, balancing permeability and solubility for (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one. Following Lipinski's Rule of Five, (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one?
The CAS number of (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one is 892627-76-8.
What is the molecular formula of (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one?
The molecular formula of (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one is C30H28N4O3.
What is the molecular weight of (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one?
The molecular weight of (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one is 492.22 g/mol.
Where can I buy (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one?
You can request a quote for (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one?
Yes, KEHONG BIO provides custom synthesis services for (4E)-4-[(1-{3-[(4-acetylphenyl)amino]-2-hydroxypropyl}-1H-indol-3-yl)methylidene]-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.