Ro 22-8515
TL;DR: Ro 22-8515 (CAS 89052-67-5) is a chemical compound with molecular formula C18H12Cl2N2O and molecular weight 342.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-chloro-6-(2-chlorophenyl)-2,4-dihydro-1H-pyrrolo[3,4-d][2]benzazepin-3-one
Also Known As: Ro 22-8515, Ro-22-8515, 8-Chloro-6-(2-chlorophenyl)-1,4-dihydropyrrolo(3,4-D)(2)benzazepin-3-(2H)one, 8-chloro-6-(2-chlorophenyl)-2,4-dihydro-1H-pyrrolo[3,4-d][2]benzazepin-3-one, 8-chloro-6-(2-chlorophenyl)-1,4-dihydropyrrolo[3,4-d][2]benzazepin-3(2H)-one
| Molecular Formula | C18H12Cl2N2O |
|---|---|
| Molecular Weight | 342.03 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 41.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 342.03265 |
| Heavy Atoms | 23 |
| Complexity | 571.0 |
Chemical Identifiers
| CAS Number | 89052-67-5 |
|---|---|
| SMILES | C1C2=C(CN=C(C3=C2C=CC(=C3)Cl)C4=CC=CC=C4Cl)C(=O)N1 |
| InChIKey | HGIIXNGRZKUQIS-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Ro 22-8515 (CAS 89052-67-5), with molecular formula C18H12Cl2N2O and molecular weight 342.03 g/mol. IUPAC: 8-chloro-6-(2-chlorophenyl)-2,4-dihydro-1H-pyrrolo[3,4-d][2]benzazepin-3-one.
Chemical Property Profile of Ro 22-8515
Property Insights of Ro 22-8515
The XLogP value of 3.2 indicates that Ro 22-8515 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.5 Ų, Ro 22-8515 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ro 22-8515 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ro 22-8515?
The CAS number of Ro 22-8515 is 89052-67-5.
What is the molecular formula of Ro 22-8515?
The molecular formula of Ro 22-8515 is C18H12Cl2N2O.
What is the molecular weight of Ro 22-8515?
The molecular weight of Ro 22-8515 is 342.03 g/mol.
Where can I buy Ro 22-8515?
You can request a quote for Ro 22-8515 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ro 22-8515?
Yes, KEHONG BIO provides custom synthesis services for Ro 22-8515 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.