PPPone structure

PPPone

TL;DR: PPPone (CAS 89011-87-0) is a chemical compound with molecular formula C27H37FN4O and molecular weight 452.30 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[4-[2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]piperazin-1-yl]-2-methyl-1-phenylpropan-1-one

Also Known As: PPPone, AE-641/30108062, 3-[4-[2-(4-Fluorophenyl)-2-(4-methyl-1-piperazinyl)ethyl]-1-piperazinyl]-2-methyl-1-phenyl-1-propanone, 3-(4-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)piperazin-1-yl)-2-methyl-1-phenylpropan-1-one, 3-{4-[2-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)-ethyl]-piperazin-1-yl}-2-methyl-1-phenyl-propan-1-one

CAS: 89011-87-0
Molecular Formula C27H37FN4O
Molecular Weight 452.30 g/mol
LogP 3.2508
Topological Polar Surface Area 30.03 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 8
Exact Mass 452.29514
Heavy Atoms 33
Complexity 874.7542

Chemical Identifiers

CAS Number 89011-87-0
SMILES CC(CN1CCN(CC1)CC(C2=CC=C(C=C2)F)N3CCN(CC3)C)C(=O)C4=CC=CC=C4

Product Overview

PPPone (CAS 89011-87-0), with molecular formula C27H37FN4O and molecular weight 452.30 g/mol. IUPAC: 3-[4-[2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]piperazin-1-yl]-2-methyl-1-phenylpropan-1-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of PPPone

XLogP
3.2508
TPSA (Topological Polar Surface Area)
30.03
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
8
Heavy Atoms
33
Complexity
874.7542
Exact Mass
452.29514
Monoisotopic Mass
452.29514
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of PPPone

The XLogP value of 3.2508 indicates that PPPone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.03 Ų, PPPone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, PPPone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of PPPone?

The CAS number of PPPone is 89011-87-0.

What is the molecular formula of PPPone?

The molecular formula of PPPone is C27H37FN4O.

What is the molecular weight of PPPone?

The molecular weight of PPPone is 452.30 g/mol.

Where can I buy PPPone?

You can request a quote for PPPone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for PPPone?

Yes, KEHONG BIO provides custom synthesis services for PPPone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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