(E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide
TL;DR: (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide (CAS 88818-74-0) is a chemical compound with molecular formula C19H14Cl2N2O2S and molecular weight 404.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2-bis(4-chlorophenyl)-2-hydroxy-N-[(E)-thiophen-2-ylmethylideneamino]acetamide
Also Known As: (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide, 2,2-bis(4-chlorophenyl)-2-hydroxy-N'-[(E)-thiophen-2-ylmethylidene]acetohydrazide, 2,2-bis(4-chlorophenyl)-2-hydroxy-N-[(E)-thiophen-2-ylmethylideneamino]acetamide
| Molecular Formula | C19H14Cl2N2O2S |
|---|---|
| Molecular Weight | 404.02 g/mol |
| LogP | 4.4411 |
| Topological Polar Surface Area | 61.69 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 404.0153 |
| Heavy Atoms | 26 |
| Complexity | 862.22687 |
Chemical Identifiers
| CAS Number | 88818-74-0 |
|---|---|
| SMILES | C1=CSC(=C1)/C=N/NC(=O)C(C2=CC=C(C=C2)Cl)(C3=CC=C(C=C3)Cl)O |
Product Overview
(E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide (CAS 88818-74-0), with molecular formula C19H14Cl2N2O2S and molecular weight 404.02 g/mol. IUPAC: 2,2-bis(4-chlorophenyl)-2-hydroxy-N-[(E)-thiophen-2-ylmethylideneamino]acetamide.
Chemical Property Profile of (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide
Property Insights of (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide
The XLogP value of 4.4411 indicates that (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.69 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide. Following Lipinski's Rule of Five, (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide?
The CAS number of (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide is 88818-74-0.
What is the molecular formula of (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide?
The molecular formula of (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide is C19H14Cl2N2O2S.
What is the molecular weight of (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide?
The molecular weight of (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide is 404.02 g/mol.
Where can I buy (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide?
You can request a quote for (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2,2-bis(4-chlorophenyl)-2-hydroxy-N'-(thiophen-2-ylmethylene)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.