F0667-0046
TL;DR: F0667-0046 (CAS 887891-75-0) is a chemical compound with molecular formula C20H18F3N3OS and molecular weight 405.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(7-methyl-2-oxo-1H-quinolin-3-yl)ethyl]-3-[4-(trifluoromethyl)phenyl]thiourea
Also Known As: F0667-0046, 1-(2-(7-methyl-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)thiourea, 1-[2-(7-methyl-2-oxo-1H-quinolin-3-yl)ethyl]-3-[4-(trifluoromethyl)phenyl]thiourea, 3-[2-(7-methyl-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]-1-[4-(trifluoromethyl)phenyl]thiourea, 7-methyl-3-(2-{3-[p-(trifluoromethyl)phenyl]thioureido}ethyl)-2(1H)-quinolinone
| Molecular Formula | C20H18F3N3OS |
|---|---|
| Molecular Weight | 405.11 g/mol |
| LogP | 4.38442 |
| Topological Polar Surface Area | 56.92 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 405.11227 |
| Heavy Atoms | 28 |
| Complexity | 1058.9644 |
Chemical Identifiers
| CAS Number | 887891-75-0 |
|---|---|
| SMILES | CC1=CC2=C(C=C1)C=C(C(=O)N2)CCNC(=S)NC3=CC=C(C=C3)C(F)(F)F |
Product Overview
F0667-0046 (CAS 887891-75-0), with molecular formula C20H18F3N3OS and molecular weight 405.11 g/mol. IUPAC: 1-[2-(7-methyl-2-oxo-1H-quinolin-3-yl)ethyl]-3-[4-(trifluoromethyl)phenyl]thiourea.
Chemical Property Profile of F0667-0046
Property Insights of F0667-0046
The XLogP value of 4.38442 indicates that F0667-0046 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.92 Ų, F0667-0046 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0667-0046 has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0667-0046?
The CAS number of F0667-0046 is 887891-75-0.
What is the molecular formula of F0667-0046?
The molecular formula of F0667-0046 is C20H18F3N3OS.
What is the molecular weight of F0667-0046?
The molecular weight of F0667-0046 is 405.11 g/mol.
Where can I buy F0667-0046?
You can request a quote for F0667-0046 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0667-0046?
Yes, KEHONG BIO provides custom synthesis services for F0667-0046 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.