Leucine thiorphan structure

Leucine thiorphan

TL;DR: Leucine thiorphan (CAS 88728-48-7) is a chemical compound with molecular formula C16H23NO3S and molecular weight 309.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-[(2-benzyl-3-sulfanylpropanoyl)amino]-4-methylpentanoic acid

Also Known As: Leucine thiorphan, Leu-thiorphan, (2-benzyl-3-mercaptopropanoyl)-L-leucine, N-[2'-Benzyl-3'-mercaptopropionyl]leucine, (2S)-2-[(2-benzyl-3-sulfanylpropanoyl)amino]-4-methylpentanoic acid

CAS: 88728-48-7
Molecular Formula C16H23NO3S
Molecular Weight 309.14 g/mol
LogP 2.2
Topological Polar Surface Area 67.4 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 8
Exact Mass 309.13986
Heavy Atoms 21
Complexity 340.0

Chemical Identifiers

CAS Number 88728-48-7
SMILES CC(C)C[C@@H](C(=O)O)NC(=O)C(CC1=CC=CC=C1)CS
InChIKey PISCFNDSARITBO-KZUDCZAMSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Organic Building Blocks (10 patents) Pharmaceutical Intermediates (14 patents)

Product Overview

Leucine thiorphan (CAS 88728-48-7), with molecular formula C16H23NO3S and molecular weight 309.14 g/mol. IUPAC: (2S)-2-[(2-benzyl-3-sulfanylpropanoyl)amino]-4-methylpentanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Leucine thiorphan

XLogP
2.2
TPSA (Topological Polar Surface Area)
67.4
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
8
Heavy Atoms
21
Complexity
340.0
Exact Mass
309.13986
Monoisotopic Mass
309.13986
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Leucine thiorphan

The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Leucine thiorphan. The TPSA of 67.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Leucine thiorphan. Following Lipinski's Rule of Five, Leucine thiorphan has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Leucine thiorphan?

The CAS number of Leucine thiorphan is 88728-48-7.

What is the molecular formula of Leucine thiorphan?

The molecular formula of Leucine thiorphan is C16H23NO3S.

What is the molecular weight of Leucine thiorphan?

The molecular weight of Leucine thiorphan is 309.14 g/mol.

Where can I buy Leucine thiorphan?

You can request a quote for Leucine thiorphan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Leucine thiorphan?

Yes, KEHONG BIO provides custom synthesis services for Leucine thiorphan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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