(4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone
TL;DR: (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone (CAS 886498-48-2) is a chemical compound with molecular formula C17H14FN3OS and molecular weight 327.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-amino-2-(4-fluoroanilino)-1,3-thiazol-5-yl]-(4-methylphenyl)methanone
Also Known As: (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone, [4-amino-2-(4-fluoroanilino)-1,3-thiazol-5-yl]-(4-methylphenyl)methanone, N2-(4-FLUOROPHENYL)-5-(4-METHYLBENZOYL)-1,3-THIAZOLE-2,4-DIAMINE, [4-amino-2-(4-fluoro-phenylamino)-thiazol-5-yl]-p-tolyl-methanone, [4-Amino-2-(4-fluorophenylamino)thiazol-5-yl]-p-tolylmethanone
| Molecular Formula | C17H14FN3OS |
|---|---|
| Molecular Weight | 327.08 g/mol |
| LogP | 4.14742 |
| Topological Polar Surface Area | 68.01 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 327.08417 |
| Heavy Atoms | 23 |
| Complexity | 841.27997 |
Chemical Identifiers
| CAS Number | 886498-48-2 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C(=O)C2=C(N=C(S2)NC3=CC=C(C=C3)F)N |
Product Overview
(4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone (CAS 886498-48-2), with molecular formula C17H14FN3OS and molecular weight 327.08 g/mol. IUPAC: [4-amino-2-(4-fluoroanilino)-1,3-thiazol-5-yl]-(4-methylphenyl)methanone.
Chemical Property Profile of (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone
Property Insights of (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone
The XLogP value of 4.14742 indicates that (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.01 Ų falls within the moderate polarity range, balancing permeability and solubility for (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone. Following Lipinski's Rule of Five, (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone?
The CAS number of (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone is 886498-48-2.
What is the molecular formula of (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone?
The molecular formula of (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone is C17H14FN3OS.
What is the molecular weight of (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone?
The molecular weight of (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone is 327.08 g/mol.
Where can I buy (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone?
You can request a quote for (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone?
Yes, KEHONG BIO provides custom synthesis services for (4-Amino-2-((4-fluorophenyl)amino)thiazol-5-yl)(p-tolyl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.