![(4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone structure](/static/products/885/885949-76-8.png)
(4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone
TL;DR: (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone (CAS 885949-76-8) is a chemical compound with molecular formula C18H18F3N3O and molecular weight 349.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4-aminophenyl)-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
Also Known As: (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone, 1865AF, (4-Aminophenyl)(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone, (4-AMINOPHENYL)(4-[4-(TRIFLUOROMETHYL)PHENYL]PIPERAZINO)METHANONE, (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]piperazino}methanone
| Molecular Formula | C18H18F3N3O |
|---|---|
| Molecular Weight | 349.14 g/mol |
| LogP | 3.25 |
| Topological Polar Surface Area | 49.57 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 349.1402 |
| Heavy Atoms | 25 |
| Complexity | 733.65674 |
Chemical Identifiers
| CAS Number | 885949-76-8 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=C(C=C2)C(F)(F)F)C(=O)C3=CC=C(C=C3)N |
Product Overview
(4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone (CAS 885949-76-8), with molecular formula C18H18F3N3O and molecular weight 349.14 g/mol. IUPAC: (4-aminophenyl)-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]methanone.
Chemical Property Profile of (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone
Property Insights of (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone
The XLogP value of 3.25 indicates that (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.57 Ų, (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone?
The CAS number of (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone is 885949-76-8.
What is the molecular formula of (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone?
The molecular formula of (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone is C18H18F3N3O.
What is the molecular weight of (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone?
The molecular weight of (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone is 349.14 g/mol.
Where can I buy (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone?
You can request a quote for (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone?
Yes, KEHONG BIO provides custom synthesis services for (4-Aminophenyl){4-[4-(trifluoromethyl)phenyl]-piperazino}methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.