![(E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one structure](/static/products/885/885191-46-8.png)
(E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one
TL;DR: (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one (CAS 885191-46-8) is a chemical compound with molecular formula C18H12ClFN2O and molecular weight 326.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3E)-3-[(2-chloro-6-fluorophenyl)methylidene]-1,2-dihydropyrrolo[1,2-a]quinazolin-5-one
Also Known As: (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one, (3E)-3-[(2-chloro-6-fluorophenyl)methylidene]-1,2-dihydropyrrolo[1,2-a]quinazolin-5-one
| Molecular Formula | C18H12ClFN2O |
|---|---|
| Molecular Weight | 326.06 g/mol |
| LogP | 4.1333 |
| Topological Polar Surface Area | 34.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 326.06223 |
| Heavy Atoms | 23 |
| Complexity | 1002.9456 |
Chemical Identifiers
| CAS Number | 885191-46-8 |
|---|---|
| SMILES | C\1CN2C3=CC=CC=C3C(=O)N=C2/C1=C/C4=C(C=CC=C4Cl)F |
Product Overview
(E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one (CAS 885191-46-8), with molecular formula C18H12ClFN2O and molecular weight 326.06 g/mol. IUPAC: (3E)-3-[(2-chloro-6-fluorophenyl)methylidene]-1,2-dihydropyrrolo[1,2-a]quinazolin-5-one.
Chemical Property Profile of (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one
Property Insights of (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one
The XLogP value of 4.1333 indicates that (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.89 Ų, (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one?
The CAS number of (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one is 885191-46-8.
What is the molecular formula of (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one?
The molecular formula of (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one is C18H12ClFN2O.
What is the molecular weight of (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one?
The molecular weight of (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one is 326.06 g/mol.
Where can I buy (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one?
You can request a quote for (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(2-chloro-6-fluorobenzylidene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.