青蒿琥酯
TL;DR: 青蒿琥酯 (CAS 88495-63-0) is a chemical compound with molecular formula C19H28O8 and molecular weight 384.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
青蒿琥酯
4-oxo-4-[[(1R,4S,5R,8S,9R,10R,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid
Also Known As: Artesunate, beta-Artesunate, Artesunic acid, Artesunato, Artesunatum
| Molecular Formula | C19H28O8 |
|---|---|
| Molecular Weight | 384.18 g/mol |
| LogP | 2.5 |
| Topological Polar Surface Area | 101.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 384.1784 |
| Heavy Atoms | 27 |
| Complexity | 623.0 |
Chemical Identifiers
| CAS Number | 88495-63-0 |
|---|---|
| SMILES | C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC(=O)CCC(=O)O)C |
| InChIKey | FIHJKUPKCHIPAT-NKHDUEHSSA-N |
Product Overview
青蒿琥酯 (CAS 88495-63-0), with molecular formula C19H28O8 and molecular weight 384.18 g/mol. IUPAC: 4-oxo-4-[[(1R,4S,5R,8S,9R,10R,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid.
Chemical Property Profile of 青蒿琥酯
Property Insights of 青蒿琥酯
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 青蒿琥酯. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 青蒿琥酯. Following Lipinski's Rule of Five, 青蒿琥酯 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 青蒿琥酯?
The CAS number of 青蒿琥酯 is 88495-63-0.
What is the molecular formula of 青蒿琥酯?
The molecular formula of 青蒿琥酯 is C19H28O8.
What is the molecular weight of 青蒿琥酯?
The molecular weight of 青蒿琥酯 is 384.18 g/mol.
Where can I buy 青蒿琥酯?
You can request a quote for 青蒿琥酯 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 青蒿琥酯?
Yes, KEHONG BIO provides custom synthesis services for 青蒿琥酯 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.