N-1,4-Benzodioxane-2-carbonyl piperazine structure

N-1,4-Benzodioxane-2-carbonyl piperazine

TL;DR: N-1,4-Benzodioxane-2-carbonyl piperazine (CAS 883535-68-0) is a chemical compound with molecular formula C13H16N2O3 and molecular weight 248.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2,3-dihydro-1,4-benzodioxin-3-yl(piperazin-1-yl)methanone

Also Known As: Not Available, 1- piperazine, (2,3-dihydrobenzo[b][1,4]dioxin-2-yl)(piperazin-1-yl)methanone, Bionet2_001597, DOXAZOSIN IMPURITY B

CAS: 883535-68-0
Molecular Formula C13H16N2O3
Molecular Weight 248.12 g/mol
LogP 0.2582
Topological Polar Surface Area 50.8 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 1
Exact Mass 248.11609
Heavy Atoms 18
Complexity 443.61743

Chemical Identifiers

CAS Number 883535-68-0
SMILES C1CN(CCN1)C(=O)C2COC3=CC=CC=C3O2

Product Overview

N-1,4-Benzodioxane-2-carbonyl piperazine (CAS 883535-68-0), with molecular formula C13H16N2O3 and molecular weight 248.12 g/mol. IUPAC: 2,3-dihydro-1,4-benzodioxin-3-yl(piperazin-1-yl)methanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of N-1,4-Benzodioxane-2-carbonyl piperazine

XLogP
0.2582
TPSA (Topological Polar Surface Area)
50.8
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
1
Heavy Atoms
18
Complexity
443.61743
Exact Mass
248.11609
Monoisotopic Mass
248.11609
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N-1,4-Benzodioxane-2-carbonyl piperazine

The XLogP value of 0.2582 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-1,4-Benzodioxane-2-carbonyl piperazine. With a topological polar surface area (TPSA) of 50.8 Ų, N-1,4-Benzodioxane-2-carbonyl piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-1,4-Benzodioxane-2-carbonyl piperazine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N-1,4-Benzodioxane-2-carbonyl piperazine?

The CAS number of N-1,4-Benzodioxane-2-carbonyl piperazine is 883535-68-0.

What is the molecular formula of N-1,4-Benzodioxane-2-carbonyl piperazine?

The molecular formula of N-1,4-Benzodioxane-2-carbonyl piperazine is C13H16N2O3.

What is the molecular weight of N-1,4-Benzodioxane-2-carbonyl piperazine?

The molecular weight of N-1,4-Benzodioxane-2-carbonyl piperazine is 248.12 g/mol.

Where can I buy N-1,4-Benzodioxane-2-carbonyl piperazine?

You can request a quote for N-1,4-Benzodioxane-2-carbonyl piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N-1,4-Benzodioxane-2-carbonyl piperazine?

Yes, KEHONG BIO provides custom synthesis services for N-1,4-Benzodioxane-2-carbonyl piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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