![(2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide structure](/static/products/883/883297-60-7.png)
(2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide
TL;DR: (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide (CAS 883297-60-7) is a chemical compound with molecular formula C16H12ClF3N4OS and molecular weight 400.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[2-[6-chloro-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-thiophen-2-ylprop-2-enamide
Also Known As: (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide, (E)-N-(2-(6-chloro-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(thiophen-2-yl)acrylamide, (E)-N-[2-[6-chloro-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-thiophen-2-ylprop-2-enamide
| Molecular Formula | C16H12ClF3N4OS |
|---|---|
| Molecular Weight | 400.04 g/mol |
| LogP | 3.8351 |
| Topological Polar Surface Area | 59.29 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 400.03723 |
| Heavy Atoms | 26 |
| Complexity | 950.4599 |
Chemical Identifiers
| CAS Number | 883297-60-7 |
|---|---|
| SMILES | C1=CSC(=C1)/C=C/C(=O)NCCC2=NN=C3N2C=C(C=C3C(F)(F)F)Cl |
Product Overview
(2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide (CAS 883297-60-7), with molecular formula C16H12ClF3N4OS and molecular weight 400.04 g/mol. IUPAC: (E)-N-[2-[6-chloro-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide
Property Insights of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide
The XLogP value of 3.8351 indicates that (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.29 Ų, (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide?
The CAS number of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide is 883297-60-7.
What is the molecular formula of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide?
The molecular formula of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide is C16H12ClF3N4OS.
What is the molecular weight of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide?
The molecular weight of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide is 400.04 g/mol.
Where can I buy (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide?
You can request a quote for (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(thiophen-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.