![(2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide structure](/static/products/883/883297-54-9.png)
(2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide
TL;DR: (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide (CAS 883297-54-9) is a chemical compound with molecular formula C18H13ClF4N4O and molecular weight 412.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[2-[6-chloro-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(3-fluorophenyl)prop-2-enamide
Also Known As: (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide, (E)-N-(2-(6-chloro-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(3-fluorophenyl)acrylamide, (E)-N-[2-[6-chloro-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(3-fluorophenyl)prop-2-enamide
| Molecular Formula | C18H13ClF4N4O |
|---|---|
| Molecular Weight | 412.07 g/mol |
| LogP | 3.9127 |
| Topological Polar Surface Area | 59.29 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 412.0714 |
| Heavy Atoms | 28 |
| Complexity | 1045.7319 |
Chemical Identifiers
| CAS Number | 883297-54-9 |
|---|---|
| SMILES | C1=CC(=CC(=C1)F)/C=C/C(=O)NCCC2=NN=C3N2C=C(C=C3C(F)(F)F)Cl |
Product Overview
(2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide (CAS 883297-54-9), with molecular formula C18H13ClF4N4O and molecular weight 412.07 g/mol. IUPAC: (E)-N-[2-[6-chloro-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(3-fluorophenyl)prop-2-enamide.
Chemical Property Profile of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide
Property Insights of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide
The XLogP value of 3.9127 indicates that (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.29 Ų, (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide?
The CAS number of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide is 883297-54-9.
What is the molecular formula of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide?
The molecular formula of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide is C18H13ClF4N4O.
What is the molecular weight of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide?
The molecular weight of (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide is 412.07 g/mol.
Where can I buy (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide?
You can request a quote for (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-N-{2-[6-chloro-8-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(3-fluorophenyl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.