2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one
TL;DR: 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one (CAS 883032-29-9) is a chemical compound with molecular formula C14H10ClFN2O and molecular weight 276.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one
Also Known As: Maybridge1_007268, S 12245, 2-(2-chloro-6-fluorophenyl)-1,2,3,4-tetrahydroquinazolin-4-one, 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one, 2-(2-Chloro-6-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one
| Molecular Formula | C14H10ClFN2O |
|---|---|
| Molecular Weight | 276.05 g/mol |
| LogP | 3.3332 |
| Topological Polar Surface Area | 41.13 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 276.04657 |
| Heavy Atoms | 19 |
| Complexity | 639.3943 |
Chemical Identifiers
| CAS Number | 883032-29-9 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=O)NC(N2)C3=C(C=CC=C3Cl)F |
Product Overview
2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one (CAS 883032-29-9), with molecular formula C14H10ClFN2O and molecular weight 276.05 g/mol. IUPAC: 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one.
Chemical Property Profile of 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one
Property Insights of 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one
The XLogP value of 3.3332 indicates that 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.13 Ų, 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one?
The CAS number of 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one is 883032-29-9.
What is the molecular formula of 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one?
The molecular formula of 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one is C14H10ClFN2O.
What is the molecular weight of 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one?
The molecular weight of 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one is 276.05 g/mol.
Where can I buy 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one?
You can request a quote for 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(2-chloro-6-fluorophenyl)-2,3-dihydro-1H-quinazolin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.