Losoxantrone
TL;DR: Losoxantrone (CAS 88303-60-0) is a chemical compound with molecular formula C22H27N5O4 and molecular weight 425.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-hydroxy-14-[2-(2-hydroxyethylamino)ethyl]-10-[2-(2-hydroxyethylamino)ethylamino]-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-8-one
Also Known As: Losoxantrone, Anthrapyrazolone, Biantrazole, bianthrazole, losoxantrona
| Molecular Formula | C22H27N5O4 |
|---|---|
| Molecular Weight | 425.21 g/mol |
| LogP | 0.6 |
| Topological Polar Surface Area | 132.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 11 |
| Exact Mass | 425.2063 |
| Heavy Atoms | 31 |
| Complexity | 596.0 |
Chemical Identifiers
| CAS Number | 88303-60-0 |
|---|---|
| SMILES | C1=CC2=C(C(=C1)O)C(=O)C3=C(C=CC4=C3C2=NN4CCNCCO)NCCNCCO |
| InChIKey | YROQEQPFUCPDCP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Losoxantrone (CAS 88303-60-0), with molecular formula C22H27N5O4 and molecular weight 425.21 g/mol. IUPAC: 6-hydroxy-14-[2-(2-hydroxyethylamino)ethyl]-10-[2-(2-hydroxyethylamino)ethylamino]-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-8-one.
Chemical Property Profile of Losoxantrone
Property Insights of Losoxantrone
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Losoxantrone. The TPSA of 132.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Losoxantrone. Following Lipinski's Rule of Five, Losoxantrone has 6 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Losoxantrone?
The CAS number of Losoxantrone is 88303-60-0.
What is the molecular formula of Losoxantrone?
The molecular formula of Losoxantrone is C22H27N5O4.
What is the molecular weight of Losoxantrone?
The molecular weight of Losoxantrone is 425.21 g/mol.
Where can I buy Losoxantrone?
You can request a quote for Losoxantrone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Losoxantrone?
Yes, KEHONG BIO provides custom synthesis services for Losoxantrone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.