Norvasc structure

Norvasc

TL;DR: Norvasc (CAS 88150-46-3) is a chemical compound with molecular formula C20H23ClN4O5 and molecular weight 434.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-O-ethyl 5-O-methyl 2-(2-azidoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Also Known As: Norvasc, Amlodipine Azido Impurity, 2-[(2-Azidoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl)-6-methyl-1,4-dihydropyridine, BAS 00136337, 3-O-ethyl 5-O-methyl 2-(2-azidoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS: 88150-46-3
Molecular Formula C20H23ClN4O5
Molecular Weight 434.14 g/mol
LogP 3.6179
Topological Polar Surface Area 122.62 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 9
Exact Mass 434.1357
Heavy Atoms 30
Complexity 921.52686

Chemical Identifiers

CAS Number 88150-46-3
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN=[N+]=[N-]

Product Overview

Norvasc (CAS 88150-46-3), with molecular formula C20H23ClN4O5 and molecular weight 434.14 g/mol. IUPAC: 3-O-ethyl 5-O-methyl 2-(2-azidoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Norvasc

XLogP
3.6179
TPSA (Topological Polar Surface Area)
122.62
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
9
Heavy Atoms
30
Complexity
921.52686
Exact Mass
434.1357
Monoisotopic Mass
434.1357
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Norvasc

The XLogP value of 3.6179 indicates that Norvasc is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 122.62 Ų falls within the moderate polarity range, balancing permeability and solubility for Norvasc. Following Lipinski's Rule of Five, Norvasc has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Norvasc?

The CAS number of Norvasc is 88150-46-3.

What is the molecular formula of Norvasc?

The molecular formula of Norvasc is C20H23ClN4O5.

What is the molecular weight of Norvasc?

The molecular weight of Norvasc is 434.14 g/mol.

Where can I buy Norvasc?

You can request a quote for Norvasc directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Norvasc?

Yes, KEHONG BIO provides custom synthesis services for Norvasc and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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