![Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate structure](/static/products/880/880451-55-8.png)
Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate
TL;DR: Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate (CAS 880451-55-8) is a chemical compound with molecular formula C18H14ClFN2O2 and molecular weight 344.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 6-chloro-4-(2-fluoroanilino)quinoline-3-carboxylate
Also Known As: SDCCGSBI-0659853.P001, BB 0222019, ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate, ethyl 6-chloro-4-(2-fluoroanilino)quinoline-3-carboxylate, 6-Chloro-4-(2-fluoro-phenylamino)-quinoline-3-carboxylic acid ethyl ester
| Molecular Formula | C18H14ClFN2O2 |
|---|---|
| Molecular Weight | 344.07 g/mol |
| LogP | 4.9476 |
| Topological Polar Surface Area | 51.22 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 344.07278 |
| Heavy Atoms | 24 |
| Complexity | 914.65936 |
Chemical Identifiers
| CAS Number | 880451-55-8 |
|---|---|
| SMILES | CCOC(=O)C1=CN=C2C=CC(=CC2=C1NC3=CC=CC=C3F)Cl |
Product Overview
Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate (CAS 880451-55-8), with molecular formula C18H14ClFN2O2 and molecular weight 344.07 g/mol. IUPAC: ethyl 6-chloro-4-(2-fluoroanilino)quinoline-3-carboxylate.
Chemical Property Profile of Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate
Property Insights of Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate
The XLogP value of 4.9476 indicates that Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.22 Ų, Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate?
The CAS number of Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate is 880451-55-8.
What is the molecular formula of Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate?
The molecular formula of Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate is C18H14ClFN2O2.
What is the molecular weight of Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate?
The molecular weight of Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate is 344.07 g/mol.
Where can I buy Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate?
You can request a quote for Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for Ethyl 6-chloro-4-[(2-fluorophenyl)amino]quinoline-3-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.