4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde
TL;DR: 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde (CAS 880076-17-5) is a chemical compound with molecular formula C18H20N4O2S and molecular weight 356.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-methyl-5-oxo-7-thiophen-2-yl-7,8-dihydro-6H-quinazolin-2-yl)piperazine-1-carbaldehyde
Also Known As: 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde, 4-(4-methyl-5-oxo-7-thiophen-2-yl-7,8-dihydro-6H-quinazolin-2-yl)piperazine-1-carbaldehyde, 4-[4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl]piperazine-1-carbaldehyde
| Molecular Formula | C18H20N4O2S |
|---|---|
| Molecular Weight | 356.13 g/mol |
| LogP | 2.03762 |
| Topological Polar Surface Area | 66.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 356.1307 |
| Heavy Atoms | 25 |
| Complexity | 797.6575 |
Chemical Identifiers
| CAS Number | 880076-17-5 |
|---|---|
| SMILES | CC1=C2C(=NC(=N1)N3CCN(CC3)C=O)CC(CC2=O)C4=CC=CS4 |
Product Overview
4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde (CAS 880076-17-5), with molecular formula C18H20N4O2S and molecular weight 356.13 g/mol. IUPAC: 4-(4-methyl-5-oxo-7-thiophen-2-yl-7,8-dihydro-6H-quinazolin-2-yl)piperazine-1-carbaldehyde.
Chemical Property Profile of 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde
Property Insights of 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde
The XLogP value of 2.03762 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde. The TPSA of 66.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde. Following Lipinski's Rule of Five, 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde?
The CAS number of 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde is 880076-17-5.
What is the molecular formula of 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde?
The molecular formula of 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde is C18H20N4O2S.
What is the molecular weight of 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde?
The molecular weight of 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde is 356.13 g/mol.
Where can I buy 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde?
You can request a quote for 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-methyl-5-oxo-7-(thiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.