5-Chloro-p-xylene-2-sulphonyl chloride structure

5-Chloro-p-xylene-2-sulphonyl chloride

TL;DR: 5-Chloro-p-xylene-2-sulphonyl chloride (CAS 88-49-3) is a chemical compound with molecular formula C8H8Cl2O2S and molecular weight 237.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-chloro-2,5-dimethylbenzenesulfonyl chloride

Also Known As: 4-chloro-2,5-dimethylbenzenesulfonyl chloride, 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride, 5-Chloro-p-xylene-2-sulphonyl chloride, Benzenesulfonylchloride, 4-chloro-2,5-dimethyl-, 4-chloro-2, 5-diMethylphenylsulfonyl chloride

CAS: 88-49-3
Molecular Formula C8H8Cl2O2S
Molecular Weight 237.96 g/mol
LogP 3.3
Topological Polar Surface Area 42.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 237.9622
Heavy Atoms 13
Complexity 270.0

Chemical Identifiers

CAS Number 88-49-3
SMILES CC1=CC(=C(C=C1Cl)C)S(=O)(=O)Cl
InChIKey JBYZPUBAISWVDI-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Analytical Reagents (2 patents) Heterocyclic Building Blocks (126 patents) Organic Building Blocks (7 patents) Pharmaceutical Intermediates (89 patents)

Product Overview

5-Chloro-p-xylene-2-sulphonyl chloride (CAS 88-49-3), with molecular formula C8H8Cl2O2S and molecular weight 237.96 g/mol. IUPAC: 4-chloro-2,5-dimethylbenzenesulfonyl chloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 5-Chloro-p-xylene-2-sulphonyl chloride

XLogP
3.3
TPSA (Topological Polar Surface Area)
42.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
13
Complexity
270.0
Exact Mass
237.9622
Monoisotopic Mass
237.9622
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5-Chloro-p-xylene-2-sulphonyl chloride

The XLogP value of 3.3 indicates that 5-Chloro-p-xylene-2-sulphonyl chloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 42.5 Ų, 5-Chloro-p-xylene-2-sulphonyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Chloro-p-xylene-2-sulphonyl chloride has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5-Chloro-p-xylene-2-sulphonyl chloride?

The CAS number of 5-Chloro-p-xylene-2-sulphonyl chloride is 88-49-3.

What is the molecular formula of 5-Chloro-p-xylene-2-sulphonyl chloride?

The molecular formula of 5-Chloro-p-xylene-2-sulphonyl chloride is C8H8Cl2O2S.

What is the molecular weight of 5-Chloro-p-xylene-2-sulphonyl chloride?

The molecular weight of 5-Chloro-p-xylene-2-sulphonyl chloride is 237.96 g/mol.

Where can I buy 5-Chloro-p-xylene-2-sulphonyl chloride?

You can request a quote for 5-Chloro-p-xylene-2-sulphonyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5-Chloro-p-xylene-2-sulphonyl chloride?

Yes, KEHONG BIO provides custom synthesis services for 5-Chloro-p-xylene-2-sulphonyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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