![1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine structure](/static/products/878/878722-16-8.png)
1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine
TL;DR: 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine (CAS 878722-16-8) is a chemical compound with molecular formula C15H12F3N3 and molecular weight 291.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[[4-(trifluoromethyl)phenyl]methyl]benzimidazol-2-amine
Also Known As: BAS 12913817, 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine, 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-amine, AT-057/43469259, 1-[[4-(trifluoromethyl)phenyl]methyl]benzimidazol-2-amine
| Molecular Formula | C15H12F3N3 |
|---|---|
| Molecular Weight | 291.10 g/mol |
| LogP | 3.6856 |
| Topological Polar Surface Area | 43.84 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 291.09833 |
| Heavy Atoms | 21 |
| Complexity | 772.9533 |
Chemical Identifiers
| CAS Number | 878722-16-8 |
|---|---|
| SMILES | C1=CC=C2C(=C1)N=C(N2CC3=CC=C(C=C3)C(F)(F)F)N |
Product Overview
1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine (CAS 878722-16-8), with molecular formula C15H12F3N3 and molecular weight 291.10 g/mol. IUPAC: 1-[[4-(trifluoromethyl)phenyl]methyl]benzimidazol-2-amine.
Chemical Property Profile of 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine
Property Insights of 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine
The XLogP value of 3.6856 indicates that 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.84 Ų, 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine?
The CAS number of 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine is 878722-16-8.
What is the molecular formula of 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine?
The molecular formula of 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine is C15H12F3N3.
What is the molecular weight of 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine?
The molecular weight of 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine is 291.10 g/mol.
Where can I buy 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine?
You can request a quote for 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine?
Yes, KEHONG BIO provides custom synthesis services for 1-[4-(trifluoromethyl)benzyl]-1H-benzimidazol-2-ylamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.