![4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline structure](/static/products/878/878263-80-0.png)
4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline
TL;DR: 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline (CAS 878263-80-0) is a chemical compound with molecular formula C18H16F2N4O2S and molecular weight 390.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[4-(2,5-difluorophenyl)sulfonylpiperazin-1-yl]quinazoline
Also Known As: 4-[4-(2,5-difluorophenyl)sulfonylpiperazin-1-yl]quinazoline, 4-[4-(2,5-Difluorobenzene-1-sulfonyl)piperazin-1-yl]quinazoline
| Molecular Formula | C18H16F2N4O2S |
|---|---|
| Molecular Weight | 390.10 g/mol |
| LogP | 2.4189 |
| Topological Polar Surface Area | 66.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 390.0962 |
| Heavy Atoms | 27 |
| Complexity | 1094.2169 |
Chemical Identifiers
| CAS Number | 878263-80-0 |
|---|---|
| SMILES | C1CN(CCN1C2=NC=NC3=CC=CC=C32)S(=O)(=O)C4=C(C=CC(=C4)F)F |
Product Overview
4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline (CAS 878263-80-0), with molecular formula C18H16F2N4O2S and molecular weight 390.10 g/mol. IUPAC: 4-[4-(2,5-difluorophenyl)sulfonylpiperazin-1-yl]quinazoline.
Chemical Property Profile of 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline
Property Insights of 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline
The XLogP value of 2.4189 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline. The TPSA of 66.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline. Following Lipinski's Rule of Five, 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline?
The CAS number of 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline is 878263-80-0.
What is the molecular formula of 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline?
The molecular formula of 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline is C18H16F2N4O2S.
What is the molecular weight of 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline?
The molecular weight of 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline is 390.10 g/mol.
Where can I buy 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline?
You can request a quote for 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-[4-(2,5-Difluorophenyl)sulfonylpiperazin-1-yl]quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.