C18H12ClFN4O structure

C18H12ClFN4O

TL;DR: C18H12ClFN4O (CAS 877808-79-2) is a chemical compound with molecular formula C18H12ClFN4O and molecular weight 354.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-chloro-11-(2-fluorophenyl)-8-oxa-12,13,15,17-tetrazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,13,15-hexaene

Also Known As: 2-chloro-7-(2-fluorophenyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine

CAS: 877808-79-2
Molecular Formula C18H12ClFN4O
Molecular Weight 354.07 g/mol
LogP 3.8892
Topological Polar Surface Area 51.97 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 1
Exact Mass 354.06836
Heavy Atoms 25
Complexity 1029.4204

Chemical Identifiers

CAS Number 877808-79-2
SMILES C1C2=C(C3=C(O1)C=CC(=C3)Cl)NC4=NC=NN4C2C5=CC=CC=C5F

Product Overview

C18H12ClFN4O (CAS 877808-79-2), with molecular formula C18H12ClFN4O and molecular weight 354.07 g/mol. IUPAC: 4-chloro-11-(2-fluorophenyl)-8-oxa-12,13,15,17-tetrazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,13,15-hexaene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of C18H12ClFN4O

XLogP
3.8892
TPSA (Topological Polar Surface Area)
51.97
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
1
Heavy Atoms
25
Complexity
1029.4204
Exact Mass
354.06836
Monoisotopic Mass
354.06836
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of C18H12ClFN4O

The XLogP value of 3.8892 indicates that C18H12ClFN4O is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.97 Ų, C18H12ClFN4O exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, C18H12ClFN4O has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of C18H12ClFN4O?

The CAS number of C18H12ClFN4O is 877808-79-2.

What is the molecular formula of C18H12ClFN4O?

The molecular formula of C18H12ClFN4O is C18H12ClFN4O.

What is the molecular weight of C18H12ClFN4O?

The molecular weight of C18H12ClFN4O is 354.07 g/mol.

Where can I buy C18H12ClFN4O?

You can request a quote for C18H12ClFN4O directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for C18H12ClFN4O?

Yes, KEHONG BIO provides custom synthesis services for C18H12ClFN4O and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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