Pyroglutamyl-3-methylhistidyl-glycine
TL;DR: Pyroglutamyl-3-methylhistidyl-glycine (CAS 87714-25-8) is a chemical compound with molecular formula C14H19N5O5 and molecular weight 337.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[(2S)-3-(3-methylimidazol-4-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]acetic acid
Also Known As: Pglu-3-Me-his-gly, Pglu-3-Me-his-gly-OH, Pyroglutamyl-3-methylhistidyl-glycine, 5-oxo-l-prolyl-3-methyl-l-histidylglycine, Glycine, N-(3-methyl-N-(5-oxo-L-prolyl)-L-histidyl)-
| Molecular Formula | C14H19N5O5 |
|---|---|
| Molecular Weight | 337.14 g/mol |
| LogP | -2.0 |
| Topological Polar Surface Area | 142.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 337.1386 |
| Heavy Atoms | 24 |
| Complexity | 526.0 |
Chemical Identifiers
| CAS Number | 87714-25-8 |
|---|---|
| SMILES | CN1C=NC=C1C[C@@H](C(=O)NCC(=O)O)NC(=O)[C@@H]2CCC(=O)N2 |
| InChIKey | GBCIQPUAKFIRCP-UWVGGRQHSA-N |
Product Overview
Pyroglutamyl-3-methylhistidyl-glycine (CAS 87714-25-8), with molecular formula C14H19N5O5 and molecular weight 337.14 g/mol. IUPAC: 2-[[(2S)-3-(3-methylimidazol-4-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]acetic acid.
Chemical Property Profile of Pyroglutamyl-3-methylhistidyl-glycine
Property Insights of Pyroglutamyl-3-methylhistidyl-glycine
The XLogP value of -2.0 indicates that Pyroglutamyl-3-methylhistidyl-glycine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 142.0 Ų indicates high polarity, suggesting Pyroglutamyl-3-methylhistidyl-glycine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pyroglutamyl-3-methylhistidyl-glycine has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyroglutamyl-3-methylhistidyl-glycine?
The CAS number of Pyroglutamyl-3-methylhistidyl-glycine is 87714-25-8.
What is the molecular formula of Pyroglutamyl-3-methylhistidyl-glycine?
The molecular formula of Pyroglutamyl-3-methylhistidyl-glycine is C14H19N5O5.
What is the molecular weight of Pyroglutamyl-3-methylhistidyl-glycine?
The molecular weight of Pyroglutamyl-3-methylhistidyl-glycine is 337.14 g/mol.
Where can I buy Pyroglutamyl-3-methylhistidyl-glycine?
You can request a quote for Pyroglutamyl-3-methylhistidyl-glycine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyroglutamyl-3-methylhistidyl-glycine?
Yes, KEHONG BIO provides custom synthesis services for Pyroglutamyl-3-methylhistidyl-glycine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.