Pyroglutamyl-histidyl-alanine
TL;DR: Pyroglutamyl-histidyl-alanine (CAS 877-16-7) is a chemical compound with molecular formula C14H19N5O5 and molecular weight 337.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]propanoic acid
Also Known As: Pglu-his-ala, Pglu-his-ala-OH, Pyroglutamyl-histidyl-alanine, 5-oxo-l-prolyl-l-histidyl-d-alanine, D-Alanine, N-(N-(5-oxo-L-prolyl)-L-histidyl)-
| Molecular Formula | C14H19N5O5 |
|---|---|
| Molecular Weight | 337.14 g/mol |
| LogP | -2.1 |
| Topological Polar Surface Area | 153.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 337.1386 |
| Heavy Atoms | 24 |
| Complexity | 526.0 |
Chemical Identifiers
| CAS Number | 877-16-7 |
|---|---|
| SMILES | C[C@H](C(=O)O)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@@H]2CCC(=O)N2 |
| InChIKey | NGNCHLZYBLGYLJ-JEZHCXPESA-N |
Product Overview
Pyroglutamyl-histidyl-alanine (CAS 877-16-7), with molecular formula C14H19N5O5 and molecular weight 337.14 g/mol. IUPAC: (2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]propanoic acid.
Chemical Property Profile of Pyroglutamyl-histidyl-alanine
Property Insights of Pyroglutamyl-histidyl-alanine
The XLogP value of -2.1 indicates that Pyroglutamyl-histidyl-alanine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 153.0 Ų indicates high polarity, suggesting Pyroglutamyl-histidyl-alanine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pyroglutamyl-histidyl-alanine has 5 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyroglutamyl-histidyl-alanine?
The CAS number of Pyroglutamyl-histidyl-alanine is 877-16-7.
What is the molecular formula of Pyroglutamyl-histidyl-alanine?
The molecular formula of Pyroglutamyl-histidyl-alanine is C14H19N5O5.
What is the molecular weight of Pyroglutamyl-histidyl-alanine?
The molecular weight of Pyroglutamyl-histidyl-alanine is 337.14 g/mol.
Where can I buy Pyroglutamyl-histidyl-alanine?
You can request a quote for Pyroglutamyl-histidyl-alanine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyroglutamyl-histidyl-alanine?
Yes, KEHONG BIO provides custom synthesis services for Pyroglutamyl-histidyl-alanine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.