Tiospirone structure

Tiospirone

TL;DR: Tiospirone (CAS 87691-91-6) is a chemical compound with molecular formula C24H32N4O2S and molecular weight 440.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

8-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione

Also Known As: tiaspirone, Tiospirona, Tiospironum, Tiospirone [INN], tiospyrone

CAS: 87691-91-6
Molecular Formula C24H32N4O2S
Molecular Weight 440.22 g/mol
LogP 4.3
Topological Polar Surface Area 85.0 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 440.2246
Heavy Atoms 31
Complexity 640.0

Chemical Identifiers

CAS Number 87691-91-6
SMILES C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NSC5=CC=CC=C54
InChIKey ZFZPJDFBJFHYIV-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.

Analytical Reagents (6 patents) Biotechnology (18 patents) Heterocyclic Building Blocks (133 patents) Organic Building Blocks (8 patents) Peptides & Amino Acids (3 patents) +1 more

Product Overview

Tiospirone (CAS 87691-91-6), with molecular formula C24H32N4O2S and molecular weight 440.22 g/mol. IUPAC: 8-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tiospirone

XLogP
4.3
TPSA (Topological Polar Surface Area)
85.0
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
31
Complexity
640.0
Exact Mass
440.2246
Monoisotopic Mass
440.2246
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tiospirone

The XLogP value of 4.3 indicates that Tiospirone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Tiospirone. Following Lipinski's Rule of Five, Tiospirone has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tiospirone?

The CAS number of Tiospirone is 87691-91-6.

What is the molecular formula of Tiospirone?

The molecular formula of Tiospirone is C24H32N4O2S.

What is the molecular weight of Tiospirone?

The molecular weight of Tiospirone is 440.22 g/mol.

Where can I buy Tiospirone?

You can request a quote for Tiospirone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tiospirone?

Yes, KEHONG BIO provides custom synthesis services for Tiospirone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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